… December 14, 2020 Research Feature Genes & Disease DNA’s resemblance to a twisted ladder … . I n fundamental research on mechanisms of synaptic plasticity —the way neurons change their circuit connections … effective in mouse models and eventually brought a candidate drug to advanced clinical trials, but it fell short …
… People Award honors Elly Nedivi’s research on cortical plasticity The Krieg Cortical Kudos Discoverer Award … and adult brain, including identification of the genes whose expression is involved, characterization of the … manipulations and the functions of activity induced candidateplasticitygenes, by using advanced state of the …
… ’s lab, which started at MIT in 1998, has discovered genes underlying plasticity – the capability of the central nervous system to … or weaker. Nedivi wanted to know how. She set out to find “candidateplasticitygenes.” Nedivi’s screens led to hundreds …
… the cellular mechanisms that underlie activity-dependent plasticity in the developing and adult brain through studies … structural dynamics, identification of the participating genes, and characterization of the proteins they encode. Her work to identify “candidateplasticitygenes” has yielded many insights, …
… leading to experience dependent changes in synaptic plasticity. Chloe Delepine Mriganka Sur Employing 3D cerebral … with a particular focus to study methods to modify neural plasticity in multiple sclerosis. Kyung-Seok Han Weifeng Xu … Bipolar Disorder (BD) related genetic variations in candidateplasticity gene 2 (CPG 2) attenuated glutamatergic …